Agaricus bisporus (ABA/ABL)

Cat# 518170-2mg

Size : 2mg

Brand : US Biological

Contact local distributor :


Phone : +1 850 650 7790


Grade
Affinity Purified

Shipping Temp
Blue Ice

Storage Temp
-20°C

ABA/ABL
Agaricus bisporus agglutinin (ABA) is an affinity-purified tetramer composed of two to four isolectins. ABA has two distinct carbohydrate binding sites, one for galactose-beta-1,3-N-acetylgalactosamine and another for galactose-beta-1,3-N-acetylglucosamine. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins.

Source:
Mushroom

Blood Specificity:
A,B - High
O - Mid
Neuraminidase - Low

Sugar Specificity:
Galactose (β-1,3), N-Acetylgalactosamine

Inhibitory Carbohydrate:
Fetuin

Divalent Ions:
None Required

Storage and Stability:
Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Source
Mushroom

Purity
Affinity Purified

Form
Supplied as a lyophilized powder.


Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.