ERBB2 probe for ISH CE/IVD - Genitourinary pathology

ERBB2 probe for ISH CE/IVD - Genitourinary pathology

 

ERBB2 is a member of the receptor tyrosine kinase family, a subset of receptor proteins that bind epidermal growth factor (EGF). ERBB2 doesn't have a binding domain itself, but stabilizes the configurations of other receptor proteins, making it easier for EGF to latch on. ERBB2 is involved in a lengthy list of important signaling cascades, as EGF is a ubiquitous mitogenic factor that stimulates cell growth in many tissue types. ERBB2's oncogenic effects first came to light in 1987, when it was found to play a major role in breast cancer metastasis. The gene remains primarily associated with breast cancer (20-30% of breast cancer patients have amplified ERBB2) but it's now also considered an important oncogene in uterine, gastric, pancreatic, colorectal and endometrial cancer, among others. 

 

 

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RUOCE / IVD
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Cat#
Description
Cond.
Price Bef. VAT
Z-2077-200
 0,2ml/20tests 
Z-2015-200
 0,2ml/20tests 
Z-2166-200
 0,2ml/20tests 
C-3032-100
 0,1ml/10tests 
C-3001-400
 0,4ml/40tests 
C-3003-40
 40tests 
C-3032-400
 0,4ml/40tests 
Z-2166-50
 0,05ml/5tests