Phytolacca americana Lectin (PWM/PWA)
The American Grape (Phytolacca americana) is a species of herbaceous perennial plants of the family Phytolaccaceae, sometimes also called Cayenne Spinach, Indian Spinach, American Phytolac, False Wine (Reunion), "Lacquer", "Lacquer Grass", "Judean Vine" or red ink plant.
It is a toxic plant. It has become invasive in part of the territories where it has been introduced, often voluntarily as a decorative plant or for other uses. It constitutes a danger for human populations and certain animals. Its concentration of toxins increases with the maturity of the plant. Its fruits are toxic for children and many animals; the plant is nevertheless still sold and cultivated as an ornamental horticultural species.
Lectin from Phytolacca americana (pokeweed) has been used:
- as a medium supplement for mononuclear cell incubation, to induce lymphocyte proliferation
- as a positive control in the study of the role of chemokine (C–C motif) ligand 2 (CCL2) in proliferation and apoptosis of decidual leukocytes
- as a supplement in the RPMI (Roswell park memorial institute) 1640 medium for peripheral blood lymphocyte cultures
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