SARS-CoV-2 - Telmisartan - Therapeutic Candidates

SARS-CoV-2 - Telmisartan - Therapeutic Candidates


Telmisartan is an angiotensin II inhibitor. It blocks the action of angiotensin II through its antagonistic function on the receptors for this substance naturally present in the body, which causes contraction of the arteries and increases arterial pressure. Telmisartan is therefore an antihypertensive drug used in the treatment of high blood pressure and chronic renal failure. Telmisartan has several advantages: its half-life is 24 hours (longer than other angiotensin II receptor antagonists) and it does not alter the metabolism of bradykinin (unlike ACE inhibitors), which avoids associated side effects such as coughing.
Studies have shown that during SARS-Cov-6 infection, alveolar cell ACE2 protein is targeted. The loss of the enzymatic action of ACE2 leads to an increase in the concentration of angiotensin II. This would be the starting point for the cytokine storm described in the most affected Covid-19 patients. For this reason, clinical studies have been initiated to test the effect of telmisartan on the development of acute respiratory distress syndrome (ARDS) in Covid-19 patients.

Search result : 177 product found

Refine your search :

RUOCE / IVD
  • Unconjugated 36
  • [3H] 1
  • all species 1
  • Biochemicals 139
  • Inhibitor/Antagonist/Agonist 27
  • Buffers and reagents 9
  • Primary antibody 1
  • Radiochemicals 1
  • rabbit 1
  • ELISA 1
  • WB 1
APPLY FILTERS
REINITIALIZE


Cat#
Description
Cond.
Price Bef. VAT
A10905-50
 50mg 
orb1308143-100mg
 100mg 
orb1308143-25mg
 25mg 
orb1226257-200mg
 200mg 
orb1308143-500mg
 500mg 
orb1308143-200mg
 200mg 
orb1902888-100mg
 100mg 
orb322556-100mg
 100mg 
orb322556-500mg
 500mg 
orb134770-1g
 1g 
orb1902885-50mg
 50mg 
orb1308143-50mg
 50mg 
orb1766265-100ug
 100ug 
orb1226257-50mg
 50mg 
orb1226257-100mg
 100mg 
orb1902887
 10mm 
orb322556-50mg
 50mg 
orb1902886-250mg
 250mg