SARS-CoV-2 Nucleocapsid Protein Monoclonal Antibody (7E1B)
Cat# bsm-41414M
Size : 100ul
Brand : Bioss
SARS-CoV-2 Nucleocapsid Protein Monoclonal Antibody (7E1B)
Applications
Reactivity
Overview | |
Catalog # | bsm-41414M |
Product Name | SARS-CoV-2 Nucleocapsid Protein Monoclonal Antibody (7E1B) |
Applications | WB, ELISA |
Reactivity | Virus |
Specifications | |
Conjugation | Unconjugated |
Host | Mouse |
Clonality | Monoclonal |
Clone # | 7E1B |
Isotype | IgG2b |
Concentration | Lot Dependant |
Purification | Purified by Protein G. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C for 12 months. |
Target | |
Swiss Prot | P0DTC9 |
Synonyms | SARS-CoV-2 Nucleocapsid Protein; SARS-CoV-2 NP; nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2]; novel coronavirus N Protein; novel coronavirus Nucleocapsid Protein; 2019-nCoV Nucleoprotein; 2019-nCoV N; 2019nCoV N; 2019-nCoV N Protein; 2019 peak N Protein; 2019-nCoV nucleocapsid protein. |
Background | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |