Anti-p63 (clone DBR16.1) Antibody
Rabbit monoclonal antibody
p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate.
p63 has also been shown to be a sensitive marker for Lung Squamous Cell Carcinoma (SqCC), with a sensitivity of ~90%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
Why detect p63?
- Useful marker in Prostate Cancer:
- Highly specific to Squamous Cell Carcinoma
- Differiates benign prostate lesions from Prostatic Carcinoma
- p 63 expression in Breast Cancer is highly sensitive and specific marker of metaplasic carcinoma
Formalin fixed paraffin embedded human Prostate Carcinoma tissue stained with p63 antibody.
|Anticorps Anti-p63 de lapin||0,5 ml||Concentrated||RMAB086R-0.5|
Medical devices for in vitro diagnostic. Read the instructions for use carefully.