New FISH probe set for glioma diagnostic
1p36/19q13 Probe Set with ZyBlack Quenching Solution
ZytoLight® Glioma 1p/19q Probe Set
Deletions
affecting the short arm of chromosome 1 (1p36) and the long arm of
chromosome 19 (19q13) arefrequently found in human gliomas and are
associated with a better survival. The new ZytoLight ® Glioma 1p/19q
Probe Set includes FISH probes for the detection of both 1p36 and 19q13
loci and the innovative ZyBlack Quenching Solution.
ZyBlack Quenching solution permet de réduire l'autofluorescence
Several types of tissue tend to emit intense autofluorescence, including brain, making it difficult to evaluate FISH results. ZyBlack Quenching Solution is a ready-to-use solution that reduces autofluorescence without adversely affecting tissue integrity or specific fluorescence signals. It can be easily incorporated into the FISH protocol by applying it after the proteolytic pretreatment.
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| 1p36 Deletion SPEC 1p36/1q25 Dual Color Probe hybridized to a glioma tissue section with 1p36 deletion as indicated by one orange signal in each nucleus |
19q13 Deletion SPEC 19q13/19p13 Dual Color Probe hybridized to a glioma tissue section with 19q13 deletion as indicated by one orange signal in each nucleus. |
| Product code | Description | Components | Tests |
| Z-2272-20 | ZytoLight Glioma 1p/19q Probe
set |
Z-2075-200 | 20 |
| Z-2076-200 | |||
| BS-0002-8 |
ZyBlack Quenching solution permet de réduire l'autofluorescence
Several types of tissue tend to emit intense autofluorescence, including brain, making it difficult to evaluate FISH results. ZyBlack Quenching Solution is a ready-to-use solution that reduces autofluorescence without adversely affecting tissue integrity or specific fluorescence signals. It can be easily incorporated into the FISH protocol by applying it after the proteolytic pretreatment.
| Without ZyBlack Quenching Solution | With ZyBlack Quenching Solution |
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| Brain tissue section hybridized with the ZytoLight SPEC 1p36/1q25 Dual Color Probe. | |