Custom service : Protein production and purification in an eukaryotic system
Use of an eukaryotic system allows to produce recombinant proteins that are submitted to post-traductional modifications, essentials to their functions.
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Indeed, all of these modifications belong to the normal maturation process that give a well-structured recombinant protein whom physical properties are different than just the gene-encoded protein.
These modifications, among others, are glycosylation, cleavage, methylation etc…
We can produce these recombinant proteins in different eukaryotic systems such as :
- Insect cells (through Baculovirus transfer)
=> Gene synthesis
=> Gene cloning
=> Polyclonals production
=> Monoclonals production